Objective A method for uncertainty analysis of salbutamol in swine tissues by liquid chromatography-tandem mass spectrometry was established to investigate the effects of each factor on the results. Methods According to the method of JJG1059.1-2012 evaluation and expression of uncertainty in measurement and the method of CNAS-GL06 guidance on evaluation the uncertainty in chemical analysis, the sources of uncertainty for determination were analyzed and each component of uncertainty was evaluated. Results The combined uncertainty was then finally obtained by synthesizing the uncertainties of various component variables:(11.05±0.77) μg/kg (k = 2). Conclusion The major affecting factors of determination results were recovery coefficient and fitting of standard curves. The experimental condition of practical measurement should be controlled strictly to improve the accuracy and reliability.
标题：液相色谱-串联质谱法测定猪肉及组织中沙丁胺醇的含量不确定度评定
英文标题：Uncertainty analysis of salbutamol in swine tissues by liquid chromatography-tandem mass spectrometry
