植物中花色苷转运蛋白研究进展
花色苷是植物重要的次生代谢产物, 因其具有高抗氧化活性受到广泛关注。目前, 关于花色苷合成代谢途径及相关转录调控机制已有了较为深入的研究, 其相关结构基因及关键转录调控因子已在多种植物中被陆续鉴定与验证, 但对于花色苷合成后的运输机制的认识仍相对缺乏。花色苷合成主要发生在内质网中, 随后运送至液泡内进行储存。花色苷的运输过程主要包括囊泡运输及链接蛋白运输两种模式, 而转运蛋白在两种运输模式中均发挥重要作用。鉴定花色苷转运相关蛋白有助于深入了解花色苷的运输机制, 完善对花色苷代谢途径的认知。本文主要针对谷胱甘肽S-转移酶(glutathione S-transferase, GST)、ATP-结合框(ATP-binding cassette, ABC)转运蛋白、多药和毒性化合物排出转运蛋白(multidrug and toxic extrusion compound transporters, MATE)和胆红素异位酶(bilitranslocase, BTL) 4类花色苷转运相关蛋白的研究进展进行了概述。
Anthocyanins are important secondary metabolites in plants, and they have received widely attention because of high antioxidant activity. To date, the pathway of anthocyanins biosynthesis and the mechanism of transcriptional regulation have been studied in depth. Structural genes and key transcriptional regulators have been successively identified in different plants. However, the transport mechanism of anthocyanins is still unclear. Anthocyaninsare synthesized in the endoplasmic reticulum, and then transported to vacuoles for storage. Anthocyanin transport includes two modes: vesicular transport and ligandin transporter. Transporters play key roles in both two modes. Identifying anthocyanin transport-related proteins is helpful to understand the transport mechanism and anthocyanin metabolic pathways. This review summarized the research status and progress of four kinds of transporters: glutathione S-transferase (GST), ATP-binding cassette (ABC) transporters, multidrug and toxic extrusion compound (MATE) transporters and bilitranslocase (BTL).
标题：植物中花色苷转运蛋白研究进展
英文标题：Research progress of anthocyanin transporters in plants
作者：
李栋 浙江大学生物系统工程与食品科学学院
李莉 浙江大学生物系统工程与食品科学学院
徐艳群 浙江大学生物系统工程与食品科学学院；浙江大学宁波研究院
罗自生 浙江大学生物系统工程与食品科学学院；浙江大学宁波研究院
中文关键词:花色苷,跨膜运输,谷胱甘肽S-转移酶,ATP-结合框转运蛋白,多药和毒性化合物排出转运蛋白,胆红素异位酶,
英文关键词:anthocyanin,transmembrane transport,glutathione S-transferase,ATP-binding cassette transporter,multidrug and toxic extrusion compound transporters,bilitranslocase,
发表日期：2019-10-17
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