高效液相色谱-质谱法测定聚碳酸酯水杯中双酚A迁移量
高效液相色谱-质谱法测定聚碳酸酯水杯中双酚A迁移量
目的建立高效液相色谱-质谱法(high performance liquid chromatography-mass spectrometry, HPLC-MS)测定聚碳酸酯(polycarbonate, PC)水杯中双酚A迁移量的方法。方法选用水、4%乙酸溶液、10%乙醇和异辛烷溶液作为食品模拟液, 准确量取迁移试验中得到的食品模拟液1 mL, 通过0.22 μm微孔滤膜后, 用高效液相色谱-质谱联用仪对双酚A进行分离测定。结果该方法相对标准偏差不大于3.24%(n=6), 回收率在87.7%~105.0%之间; 检出限为 1 μg/L。结论该方法样品前处理方法简便, 检出限高, 操作简单, 线性关系好, 适合于PC水杯及不同塑料制品中迁移双酚A的检测分析。
ObjectiveTo establish a method for determination of the migration of bisphenol A in polycarbonate (PC) cups by high performance liquid chromatography-mass spectrometry (HPLC-MS) method. MethodsWater, 4% acetic acid solution, 10% ethanol and isooctane solution were used as food simulation solution. The 1 mL of the food simulating solution obtained in the migration test was accurately measured, and passed through a 0.22 μm microporous membrane, and the bisphenol A was separated by HPLC-MS. ResultsThe relative standard deviations of the method were less than 3.24% (n=6), the recovery rates were 87.7%-105.0%; and the detection limit was 1 μg/L. ConclusionThe method has the advantages of simple sample preparation method, high detection limit, simple operation and good linear relationship, which is suitable for detection and analysis of migration of bisphenol A in PC water cups and different plastic products.
标题：高效液相色谱-质谱法测定聚碳酸酯水杯中双酚A迁移量
英文标题：Determination of migration of bisphenol A in polycarbonate cup by high performance liquid chromatography-mass spectrometry
作者：
杨光 黑龙江省质量监督检测研究院
王佳祥 黑龙江省质量监督检测研究院
王珊珊 黑龙江省质量监督检测研究院
中文关键词:高效液相色谱-质谱法,聚碳酸酯水杯,双酚A,
英文关键词:high performance liquid chromatography-mass spectrometry,polycarbonate water cup,bisphenol A,
发表日期：2018-10-10
页:
[1]